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How to Prepare for Your First Ultrasound-Guided Infiltration

Published on 2026-05-22

First Infiltration: Where to Start?

Receiving your first ultrasound-guided corticosteroid injection can feel intimidating, but proper preparation makes all the difference. At Dr Sébastien Bolduc's Musculoskeletal Medicine Clinic, we guide each patient step by step. Here is everything you need to know before your appointment.

What to Bring on the Day

On the day of your appointment at 8131 boul. Cousineau in Saint-Hubert, bring the following:

  • Your Quebec health insurance card (RAMQ) and private insurance card if applicable
  • A signed prescription or referral form from your referring physician
  • A complete list of your current medications including dosages
  • Comfortable clothing that allows easy access to the treatment area (shorts for the knee, tank top for the shoulder)
  • Results of any prior imaging studies (MRI, ultrasound, X-ray) if relevant

Medications to Stop Before Infiltration

Certain medications increase the risk of bleeding or infection. It is generally recommended to stop:

  • Anticoagulants and antiplatelet drugs: warfarin (Coumadin), apixaban (Eliquis), rivaroxaban (Xarelto), clopidogrel (Plavix) — only if confirmed by your prescribing doctor
  • Non-steroidal anti-inflammatory drugs (NSAIDs): ibuprofen (Advil, Motrin), naproxen (Aleve), diclofenac (Voltaren) — typically 48 to 72 hours before
  • Supplements: fish oil, ginkgo, and high-dose garlic can thin the blood

Never stop a medication without discussing it with the prescribing physician. Low-dose aspirin for cardiac prevention is usually continued.

What to Expect During the Procedure

The ultrasound-guided infiltration usually takes 10 to 15 minutes. Dr Bolduc uses an ultrasound probe to visualize the needle and target area in real time, increasing precision and reducing discomfort. You will feel a brief sting when the needle is inserted, followed by pressure as the medication (typically cortisone) is injected.

After the Infiltration: The First Few Days

In the 24 to 48 hours following the injection, it is normal to experience a temporary inflammatory flare called a "flare reaction." To manage it:

  • Apply ice to the area for 15 minutes, 3 to 4 times a day
  • Avoid strenuous activity and sports for 3 to 7 days as recommended
  • Do not take NSAIDs unless instructed, as they may counteract the cortisone effect
  • Watch for signs of infection: increasing redness, local warmth, fever — consult promptly if they appear

Contraindications

Infiltration is not recommended in cases of active infection in the treatment area, unexplained fever, known allergy to cortisone or local anesthetic, or pregnancy (unless cleared by a physician). Dr Bolduc will review these factors during your consultation.

Frequently Asked Questions

How long does a cortisone infiltration last?

The effect varies depending on the condition and the area treated, but it typically lasts from several weeks to several months. Some patients feel relief within 48 to 72 hours, with maximum effect reached in 7 to 10 days.

Can I drive after an infiltration?

In most cases, yes. However, if the injection is in your right knee or ankle (the driving leg), it is safer to have someone accompany you. Dr Bolduc will give you a personalized recommendation after the procedure.

Does the infiltration hurt?

Discomfort is generally minimal. The initial needle prick feels similar to a blood draw. Using ultrasound guidance, Dr Bolduc targets the area precisely, which reduces pain and risk.

How many infiltration sessions can I have?

There is no strict limit, but generally no more than 3 to 4 injections per year on the same joint are recommended. Excessive cortisone use can weaken tendons and cartilage long-term. Your doctor will determine the optimal number based on your condition.