What to Do After a Cortisone Injection: Post-Procedure Care Guide
Published on 2026-05-22
Understanding Ultrasound-Guided Cortisone Injections
Cortisone (corticosteroid) injections are a common medical procedure performed at the office of Dr Sébastien Bolduc at the Clinique de médecine musculo-squelettique to treat various inflammatory conditions: tendinitis, bursitis, osteoarthritis, carpal tunnel syndrome, and other musculoskeletal pathologies. The injection is performed under ultrasound guidance, allowing the physician to visualize the needle in real-time and deposit the medication exactly where it is needed.
Although the injection itself is a simple and quick procedure (a few minutes), the period that follows is crucial to maximize its effectiveness and minimize the risk of complications. Here is everything you need to know to properly manage the days following your injection.
The First 24 to 48 Hours: Rest and Ice
Immediately after the injection, it is normal to feel mild discomfort or a sensation of pressure at the injection site. Here are the instructions to follow:
- Relative rest: avoid any intense physical activity for at least 48 hours. You may resume light daily activities (walking, light housework) the next day, but listen to your body.
- Ice application: apply an ice pack (wrapped in a cloth) to the injected area for 15 to 20 minutes, 3 to 4 times a day for the first 48 hours. Ice reduces local inflammation and soothes pain.
- Keep dry: keep the injection site dry for 24 hours (no shower or hot bath). A small protective bandage may be applied.
- Elevation: if the injection is in a lower limb (knee, ankle), elevate it when sitting or lying down to reduce swelling.
It is common to experience a transient inflammatory flare (flare reaction) within 24 to 48 hours after the injection. This is a normal reaction related to the needle micro-trauma and corticosteroid crystallization. Ice and rest are usually sufficient to control it.
The Following Days (Day 3 to Day 14)
From the third day onward, the cortisone begins to take full effect. Pain decreases significantly. This is the time to gradually resume your activities, with caution:
- Resume normal daily activities according to your tolerance.
- Avoid impact sports, running, jumping, and heavy lifting for 7 to 10 days.
- Do not perform maximal effort on the treated area before 2 weeks.
- If physiotherapy is prescribed, begin it generally after 5 to 7 days, when the anti-inflammatory effect is at its peak.
Return to Sports and Normal Activities
The return to sports must be gradual. For shoulder, knee, or Achilles tendon injections, allow approximately 2 to 4 weeks before resuming full sports activity. Your physician will provide a specific timeline adapted to your condition. It is important to understand that the injection treats inflammation but does not cure the underlying cause — a rehabilitation program (physiotherapy, eccentric exercises) is often necessary to prevent recurrence.
Warning Signs and Possible Complications
Consult promptly if you experience any of the following signs:
- Intense pain that increases rather than decreases after 48 hours
- Significant redness, local heat, or fever (possible infection)
- Worsening swelling
- Numbness or weakness in the treated limb
- Skin color changes around the injection site
For any questions or concerns, Dr Sébastien Bolduc and his team at the Clinique de médecine musculo-squelettique (8131 boul. Cousineau, Saint-Hubert) remain available. Do not hesitate to contact us if you have any doubt about your recovery.
Frequently Asked Questions
Can I shower after a cortisone injection?
It is recommended to wait 24 hours before wetting the injection site. After that, you can shower normally. Avoid hot baths, pools, and spas for 48 hours to reduce the risk of infection.
How long does it take for cortisone to take effect?
The anti-inflammatory effect of cortisone typically begins within 24 to 72 hours, with peak effectiveness between day 3 and day 7. The effect can last from a few weeks to several months depending on the condition being treated and the dose administered.
Why is my pain worse after the injection?
A transient inflammatory flare (flare reaction) occurs in about 10 to 20% of cases within 24 to 48 hours after the injection. This is a normal reaction related to the needle and corticosteroid crystallization. Ice and rest help control this reaction, which usually resolves on its own.
How many injections can I receive in the same area?
As a general rule, cortisone injections are limited to 3 per year at the same site to avoid the risk of tendon or skin atrophy. Your physician will assess the risk-benefit ratio in your case and may suggest alternatives such as PRP or shockwave therapy if injections are insufficient.